FIT screening

Colorectal cancer (CRC) is one of the most frequently diagnosed cancers. The good news is that CRC incidence and mortality can be reduced significantly if detected early enough.

Faecal immunochemical tests (FIT) are non-invasive and can detect blood in stool invisible to the naked eye. Due to its simplicity, FIT is currently considered the best non-invasive test for CRC screening.

Invest a little time in your own health by taking the FIT to prevent or detect colon cancer early on.
For further information, please visit our ‘FIT for screening’ website www.fitscreening.eu/patients

Sysmex XT-2000

XT-1800i

  • Sysmex’s unique fluorescence flow cytometry (FFC) for high quality blood cell analysis
  • Full 5-part differential WBC analysis with excellent reliability and 80 samples/hour
  • IG count delivers valuable information with diagnostic significance
  • Ready-to-use system with minimum maintenance
  • Proactive user support with SNCS and online quality control

XT-1800i – unique FFC technology, compact and reliable, with true IG count

The XT-1800i haematology analyser uses our unique fluorescence flow cytometry (FFC) technology. FFC looks at RNA/DNA content, cell size and inner cell complexity rather than cell size alone. This generates remarkably accurate results and a superb WBC differential. Review rates and turnaround time are reduced due to specific fluorochrome labelling. The XT-1800i offers true quantitative IG counting instead of the flagging delivered by other technologies. And it’s very precise for RBC and PLT parameters thanks to hydrodynamic focusing.

The analyser is practical and can be adapted to your own particular workflow. Because it is ready-to-use immediately and has a quick shutdown, you’ll have more time for other jobs. You will appreciate its cost-effective reagent consumption, and the fact that you can adapt the diagnostic sensitivity to your own laboratory needs through its unique Q-flags. You can also attach it to our network communication system for online quality control.

True IG Count

True IG Count

Your XT-1800i analyser offers increased analytical possibilities as it offers a classic 5-part differential and a true immature granulocyte count, with superior clinical utility than the flagging offered by other technologies. IG supports the quick detection of inflammation and infections, and lets you monitor later treatment. It also lets you reduce the number of smears because in most cases there is no longer a need for manual counting of IG.  

Flexible and adaptable (even in diagnostics)

Flexible and adaptable (even in diagnostics)

The XT-1800i is available with a range of options. You can adapt it to the requirements of your laboratory. As standard, samples are processed at a stable speed of 80 samples/h regardless of the profile analysed. A STAT function lets you analyse emergency samples immediately. It has a low aspiration volume of just 85μL in manual mode.

Sample-specific selective testing adapts the reagent consumption to actual analytical needs. Even if the system is operated offline, you maintain selective sample analysis by using the work list function.

A 50-tube cap-piercing auto-sampler with continuous feeding of samples offers walk-away automation. No matter whether a manual or an automated bar code reader is used, adequate positive sample identification gives confidence.

Compact yet powerful

Compact yet powerful

Space comes at a premium in labs, so we looked at ways to reduce this device’s footprint and intrusion. Thanks to its small laser and clever use of reagents, this true 5-part differential analyser is one of the most compact in its class.

Reliable and ready when you are

Reliable and ready when you are

The last thing you want is to wait for your machines to be ready. Thanks to its efficient semiconductor laser, the XT-1800i is ready to use when needed. We use only high-quality components in manufacturing to ensure your device lasts a long time. And because of our attention to detail, you can count on continuous smooth operation even when analysing with the small aspiration volume.  

The only daily preventive maintenance you or your staff will have to perform is to administer the cleaning reagent for the fully automated shutdown sequence at the end of your day.

Fluorescence flow cytometry can really help you

Fluorescence flow cytometry can really help you

Fluorescence flow cytometry is used to analyse physiological and chemical properties of cells. It can also be used to analyse other biological particles in urinalysis analysers. It provides:

  • Information about cell size and structure
  • Information about a cell’s interior

In flow cytometry, we examine cells and particles while they are flowing through a very narrow flow cell.

First a blood sample is aspirated and proportioned, then diluted to a pre-set ratio and labelled with a proprietary fluorescence marker that binds specifically to nucleic acids.

Next the sample is transported into the flow cell. The sample is illuminated by a semiconductor laser beam, which can separate the cells using three different signals:

  • forward scattered light (forward scatter or FSC)
  • side scattered light (side scatter or SSC)
  • side fluorescence light (side fluorescence or SFL).

The intensity of the forward scatter indicates the cell volume. The side scatter provides information about the cell content, such as nucleus and granules. The side fluorescence indicates the amount of DNA and RNA present in the cell.

Cells with similar physical and chemical properties form a cluster in a graph known as a scattergram.

The principle of fluorescence flow cytometry is used in different analysers for haematology and urinalysis. For blood cell counts we use fluorescence flow cytometry, e.g. for the WBC and differential, for NRBC counting and reticulocyte measurement.

In urinalysis analysers, fluorescence technology is also used for counting bacteria, red blood cells, white blood cells and other elements. 

Specifications

Specifications

Technologies

fluorescence flow cytometry: WBC DIFF, IG,

DC sheath flow method: RBC, HCT, PLT

cyanide-free SLS method: HGB

 

Parameters

WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT

NEUT(%,#) LYMPH(%,#), MONO(%,#), EO(%,#), BASO(%,#),

IG(%,#), RDW-SD, RDW-CV, MPV, P-LCR, PDW, PCT

research parameters: OTHER(%,#)

 

Throughput

stand-alone: 80 samples/hour

twin: 160 samples/hour

 

Aspiration volume

150μL for sampler/manual closed mode

85μL for manual open mode

40μL sample volume for capillary mode

 

Data storage

10,000 samples (incl. graphics)

5,000 patients’ information

1,000 selective test orders

 

Quality control

20 QC files, 1 XbarM file (300 data points)

optional: daily external QC IQAS Online

Interfaces

Host (Ethernet or serial),

graphic printer (parallel or USB)

Standard modules

XT-PRO, XT-IG Master

Options

rack sampler for 50 sample tubes

bar code reader for sampler mode

manual cap piercer unit, hand-held bar code reader

XT-TWIN (TCM)

 

Dimensions/weights

wxhxd [mm]/[kg]

530x630x720/59 (main unit with sampler)

280x400x355/17 (pneumatic unit)

305x85x345/8 (IPU: information-processing unit)

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