PATIENT PORTAL

Sysmex is active in a broad spectrum of healthcare areas. In addtion to information for healthcare professionals we also provide applied information for privat individuals seeking assistance in our
areas of expertise. 

At the moment we provide guidance and background info on breast cancer . We welcome you to visit http://www.breast-cancer-diagnosis.co.uk/

  • One Step - One Decision
    One Step - One Decision

OSNA – Molecular Detection of Metastases in Lymph Nodes

Lymph node status is one of the most important prognostic factors in many cancers and a key criterion for surgical and therapeutic decisions. Great importance is therefore attached to the reliable and accurate analysis of the lymph node tissue for detection of metastases.
OSNA® – One Step Nucleic Acid Amplification – is a highly automated molecular assay. The reaction procedure is based on specific isothermal technology to amplify nucleic acid (RT-LAMP) and allows the detection of Cytokeratin 19 (CK19) mRNA expression. CK19 is an epithelial cell marker and is not normally present in lymph node tissue. The expression rate of CK19 mRNA correlates with the size of the metastatic foci. The benefits of using OSNA® include:

  • Prompt availability of results
  • Automated and standardised test procedure
  • High levels of sensitivity and specificity
  • The entire lymph node can be analysed
  • Simple test performance even without molecular biological expertise

 

OSNA® is CE-certified and complies with the requirements of Directive 98/79/EC for in-vitro diagnostic medical devices and is thus approved for use in diagnostics.

Breast Cancer

Colon Cancer

Solution for magnetic sentinel lymph node localisation

Clinical evidence

Oncology Overview

Go back to the overview of Oncology

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