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Platelet detection and the importance of a reliable count
Platelet formation: As described by Wright for the first time, platelets are small non-nucleated ‘extensions’ of megakaryocytes – the platelet precursor cells present in bone marrow that develop from a stem cell in the course of thrombopoiesis (platelet generation).
- Diagnostic Perspectives
Platelet morphology and IPF during treatment with haemodialysis
In patients treated with haemodialysis (HD), the interaction with the dialysis membrane can disturb haemostatic balance. Interaction of platelets with the membrane can lead to platelet activation and adhesion, which both affects membrane performance and the viability of platelets. By looking at platelet characteristics and morphology, as well as markers of platelet activation, this process can be characterized in more detail.
- Xtra Article
Quantitative and qualitative monitoring of erythropoiesis with RET-He even on XE-2100 and XT-2000i
Detection of functional iron deficiency is a challenging task. Iron deficiency is a major but highly underestimated health problem worldwide, which in the long run can lead to iron deficiency anaemia and impaired erythropoiesis. Assessment of erythropoietic activity is therefore of prime importance in anaemia diagnostics.
SEED: Blast cells – a diagnostic heavyweight
The detection of blast cells in the peripheral blood is considered extremely important, and great responsibility is placed on the investigating laboratory. As well as informa¬tion on the physiology, this SEED article describes the possible causes of the release of blast cells into the blood, the char¬acteristics by which they can be identified and how further diagnosis is carried out.
- Body Fluid
SEED: Body fluid cell counts – how to perform and interpret the results
This SEED article is meant to explain the findings focused on cell count and differentiation for pleural, ascitic, cerebrospinal and synovial fluid as well as for CAPD. Traditionally, body fluid counts are performed by manual counting under a microscope using a haemocytometer, but laboratories now have the option of automating their manual processes using automated haematology or urinalysis analysers. This SEED summarises the advantages and disadvantages of haemocytometry and Sysmex analysers and explains briefly the XN-BF mode.