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Platelet formation: As described by Wright for the first time, platelets are small non-nucleated ‘extensions’ of megakaryocytes – the platelet precursor cells present in bone marrow that develop from a stem cell in the course of thrombopoiesis (platelet generation).
To define whether a patient’s results are considered ‘normal’ or ‘healthy’ reference intervals are needed. In this article the prerequisites for reference intervals and different approaches for determination of those are described. Sysmex provides a list of scientific publications that inform about the reference intervals for Sysmex analysers, which can be found in this article.
Cerebrospinal fluid as sample material requires particular attention at all times, from sample collection and transport to laboratory diagnostics. Upon arrival at the laboratory, the CSF sample must be processed quickly with great care and expertise so that the analysis results provide the information needed by the physician for treatment decisions. In this article you find a summary of all lab procedures with a focus on cell count and differentiation.