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Malaria is a detectable, preventable, and curable disease, but the burden on global health is still very high. This SEED article discusses a broad range of aspects, from the latest figures from the World Health Organisation and the Plasmodium life cycle to the limitations of stablished diagnostic tests, and how new technologies, such as the Sysmex XN-31 analyser, can enlighten the way towards malaria elimination.
During HSCT patients suffer from many critical conditions such as thrombocytopenia or infections, as well as it is necessary to closely monitor the engraftment. This white paper explains how a Sysmex haematology analyser can answer your clinical demands.
A deeper insight about an activation of the immune response of patients can be acquired from newly available diagnostic parameters that support differentiation between inflammation and infection, different pathogenic causes of infection (viral versus bacterial) and different types of immune response: early innate, cellular or humoral immune response.
There has been an increase in the use of neoadjuvant systemic therapy (NAST) in breast cancer patients in recent years. The main indications include shrinking the primary tumour, thus reducing the extent of surgery, or enabling breast conserving surgery instead of mastectomy. Moreover, it allows an assessment of the tumour’s response to systemic therapy.
Platelet formation: As described by Wright for the first time, platelets are small non-nucleated ‘extensions’ of megakaryocytes – the platelet precursor cells present in bone marrow that develop from a stem cell in the course of thrombopoiesis (platelet generation).
In patients treated with haemodialysis (HD), the interaction with the dialysis membrane can disturb haemostatic balance. Interaction of platelets with the membrane can lead to platelet activation and adhesion, which both affects membrane performance and the viability of platelets. By looking at platelet characteristics and morphology, as well as markers of platelet activation, this process can be characterized in more detail.